Respiratory syncytial virus (RSV) community-acquired pneumonia (CAP) in a hospitalized adult with human immunodeficiency virus (HIV) mimicking influenza A and Pneumocystis (carinii) jiroveci pneumonia (PCP)

Non-chemotactic influence of CXCL7 on human phagocytes. Modulation of antimicrobial activity against L. pneumophila.

Authors: González-Cortés C, Diez-Tascón C, Guerra-Laso JM, González-Cocaño MC, Rivero-Lezcano OM Abstract We have investigated the role of CXCL7 in the immune response of human phagocytes against the intracellular bacteria Mycobacterium tuberculosis and Legionella pneumophila. We have observed that polymorphonuclear neutrophil (PMN) chemotaxis induced by the supernatants of infected monocyte derived macrophages (MDM) may be attributed to CXCL8 rather than CXCL7, although both chemokines are present in large quantities. We have also found that CXCL7 is present not only in the supernatants of MDM, but also in the supernatants of PMN of some, but not all, individuals. Western blot analysis revealed that, in both MDM and PMN supernatants appeared two bands with molecular weights c...

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Legionella steelei sp. nov. isolated from human respiratory specimens in California and South Australia.

Authors: Edelstein PH, Edelstein MA, Shephard LJ, Ward KW, Ratcliff RM Abstract Legionella-like bacteria were isolated from the respiratory tract of two humans in California and South Australia, but not thought to cause disease. These bacteria, strains F2632 and IMVS-3376, were found to have identical Legionella macrophage infectivity potentiator (mip) sequences, and were therefore further characterized to determine their genetic and phenotypic relatedness and properties. Both of these Gram-negative bacterial strains grew on buffered charcoal yeast extract medium, were cysteine auxotrophs, and made a characteristic diffusible bright yellow fluorescent pigment, with one strain making a late appearing colony bound blue white fluorescent pigment. Optimal in vitro growth temperature wa...

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